Serrapeptase, nattokinase, wobenzym review for endometriosis pain

In my research about endometriosis pain management, I have read about some endo bloggers who used systemic enzymes with great success. The ones most talked about are serrapeptase, nattokinase and wobenzym. Those who have tried them reported being finally pain free so I did more research and decided to take them.

These are the ones I am currently taking on a daily basis. They must be taken on an empty stomach (I take them 90 minutes before breakfast and just before going to sleep at night). You can buy them on amazon.

systemic enzymes

Endo pain is usually worst for me during menstruation, when the pain level is at 10 for up to 7 days, during those days I usually need a morphine injection (at the hospital) or a 100mg diclofenac suppository every day and every night.

These are my experiences taking systemic enzymes:

The 1st month:

  • I took 2 tablets of serrapeptase 90 minutes before breakfast (every day during the whole month).
  • Period is very heavy as before with clots. Pain reduction during menstruation was 30%. I still had to take my usual pain killer for 3 days (100mg diclofenac suppository) in addition to using a heated wheat pad for pain relief.

The 2nd month:

  • I took 2 tablets of serrapeptase and 2 tablets of nattokinase together 90 minutes before breakfast (every day during the whole month).
  • Period is heavy and still with clots. Pain reduction during menstruation was 70%. I didn’t need any prescription pain medication. I only had to take paracetamol and 8mg co-codamol for 3 days in addition to using a heated wheat pad for pain relief.

The 3rd month:

  • I took 2 tablets of serrapeptase, 2 tablets of nattokinase, 2 tablets of wobenzyme, all together once in the morning (90 minutes before breakfast) and the same dosage again before going to bed at night (every day during the whole month). This is the dosage I still take as of today (total of 12 enzymes every day).
  • Period is now normal but still have clots. Pain reduction during menstruation was 90%. I didn’t need to take any pain relief medication at all (not even paracetamol). I just used a heated wheat pad for pain relief. 70% of the pain I felt were like normal period pain, there was one occasion when I had intense endo pain at level 8, but it only lasted for 10 minutes and was eased with the heated pad.

Intense pain is a sign of inflammation and as systemic enzymes deal directly with the inflammation, it is no wonder that they are able to dramatically reduce the endo pain that occurs during menstruation. I think that the enzymes are tackling all my endo pain during the whole month that are caused by inflammation. There are however other endo pain (not caused by inflammation), which I still have during the rest of the month, that I am still in the process of finding natural relief for – at this time I am using a heated wheat pad and 2 paracetamol with one 15mg co-codamol tablets as needed (my prescription was initially a 2x30mg co-codamol, but since last month I found that I only need half of one tablet so I just divide the 30mg tablet into 2).

So to recap, I am very happy with serrapeptase, nattokinase and wobenzym. I find them miraculous for reducing endo pain that are caused by inflammation. They have other benefits (reducing internal endo scarring, preventing further adhesion, clearing blocked tubes etc) which are bound to help the endo condition in general, however they are not a cure (there is no cure according to the medical profession) so my research continues.

Systemic enzyme dosage is a very personal thing as it depends on the severity of your condition and pain. All articles that I have read recommend to start with a high dosage and then reduce the dosage once you are pain free. In this article, Dr James Howenstine MD recommends 15 or more enzyme tablets a day for patients with endometriosis.

Have you tried systemic enzyme for your endometriosis and had success with it? Please share your experiences. Or did you find something else that is also natural that is helping you a lot?

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